Novartis created its first DPP4 drug candidate in 1996 and by 1998 had invented Galvus.
He said much more work was now needed to test this new drug candidate.
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After screening dredges up a promising drug candidate, combinatorial chemistry takes a hand.
Its lead drug candidate is Flurizan, a therapeutic drug to treat Alzheimer's disease.
Its lead drug candidate will remain Provenge, a vaccine to treat prostate cancer.
When you wanted a new natural-product drug candidate, you could basically Google it.
Scientists at Koronis Pharmaceuticals, a small private biotech company in Seattle, have a drug candidate that does just that.
ImmunoGen said T-DM1 is the most advanced drug candidate that uses its technology.
Pirfenidone is InterMune's investigational drug candidate for the treatment of patients with idiopathic pulmonary fibrosis to reduce decline in lung function.
The fund's first investment was in BioCryst Pharmaceuticals, which needed additional funding to pursue clinical trials for its antiviral drug candidate Peramivir.
The other drug candidate is for the treatment of peripheral T-cell lymphoma.
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Earlier this year a drug candidate from Sugen, a biotech that Pharmacia bought in 1999, fell through, but more are on the way.
The pill, SCH 530348, could be the most important experimental drug candidate Schering is testing and might eventually generate billions of dollars in sales.
With Isis, Symphony and some co-investors are creating a new entity, Symphony GenIsis, that will take ownership of a promising cholesterol-lowering drug candidate in Isis' pipeline through its Phase 2b trials.
Rinat, a spinoff of Genentech, had been in a bidding war to partner with one of nine interested pharmaceutical firms for a promising but very early stage drug candidate to treat Alzheimer's.
The fund's first investment was in BioCryst Pharmaceuticals (nasdaq: BCRX - news - people ), which needed additional funding to pursue clinical trials for its antiviral drug candidate Peramivir.
Chi-Med was able to skip the early-stage trial with its Crohn's disease drug candidate because its active ingredient, the herb andrographolide, has been used in China for decades to treat respiratory infections and inflammation.
Rinat, a spinoff of Genentech (nyse: DNA - news - people ), had been in a bidding war to partner with one of nine interested pharmaceutical firms for a promising but very early stage drug candidate to treat Alzheimer's.
If the drug candidate is derived from an herbal medicine that is legally marketed and hasn't caused safety problems, it may be able to skip the early-stage safety trial and go right to midstage clinical trials, which measure efficacy and determine proper dosing.
The reason for the enthusiasm: BioCryst's influenza neuraminidase inhibitor drug candidate, peramivir, received prominent and positive mention in a New York Times article about how some discarded drug candidates may have new possibilities in treating the H5N1 avian influenza that has broken out in Southeast Asia, which many public health officials fear could develop into a global pandemic.
Auroras scientists use a fluorescent marker to tell them whether a candidate drug molecule has had an effect on the target molecule.
They will also do on-site drug tests and verify a candidate's credentials.
She said she recently treated a woman whose breast cancer initially tested negative for a mutation that causes elevated levels of a cancer-promoting protein called HER2, which would have made her a candidate for the drug Herceptin.
Being cheaper made Gilead the subject of rumors it could be a buyout candidate for an even bigger drug maker looking to fill a dwindling pipeline.
You only have about three hours to get to the emergency room, go through the admission process and get evaluated before the doctors can figure out if you are a candidate for the clot busting drug that could save you from devastating disability.
From all of this, Healy ascertains that any drug approved since 1990 should be considered a possible candidate for late side-effects.
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For instance, if you want a drug that affects just one kind of serotonin receptor, you test candidate compounds against the other 13 known receptors, too.
Last fall, Texas Gov. Rick Perry, a candidate for the 2012 GOP presidential nomination, said he thought the drug war violence had become so dire that U.S. troops could be sent into Mexico.
The Liberal Democrat candidate for the Avon and Somerset police elections says he wants more help for drug addicts.
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