Judge Letts saw Michael not as a hopeless, drug-using criminal, but as an individual with a disease in need of help.
Kadcyla was developed by South San Francisco-based Genentech using drug-binding technology licensed from Waltham, Mass.
More important, research-based drug firms are using a variety of tactics to make the patent cliff slope more gently.
But the concern has led doctors to back off using the drug-coated stents in every case, leading to the slumping sales of these devices.
Merck (nyse: MRK - news - people ), the world's third-largest drug company, is using gene expression arrays, also known as DNA chips, to keep clinical duds from reaching expensive animal or human trials.
Like many drug companies, Bristol-Myers had been using incentives to entice wholesalers into stocking up on its drugs.
Giusti founded the Multiple Myeloma Research Foundation in 1998 with the goal of using her drug industry know-how to get treatments developed.
In America and the UK there are anti-drug programmes such as Narcinon, using a regime of exercise, saunas and vitamin B the church claims it has a 75% success rate.
Hartwell and Friend ran a drug-discovery program at the Hutchinson Center using funds from Merck (nyse: MRK - news - people) and the National Cancer Institute before Rosetta was founded.
Also uncertain is whether the 2006 Tour de France winner can clear his name after officials accused him of allegedly using a performance-enhancing drug--a charge he denies.
But the drug ran into trouble: it was pulled soon after entering the U.S. market six years ago, when a few patients using the drug developed a life-threatening brain infection.
That won't prevent doctors from using the drug, says Roman Perez-Soler of Montefiore Medical Center in New York.
Using only one cholesterol-lowering drug simplifies the studies.
Gregg W. Stone, a professor of medicine at Columbia University and the author of an analysis of Boston Scientific's stent published in the New England Journal, says that is worried that doctors have pulled back too much from using drug coated stents, in even off-label uses.
However, they suggested using the drug may need to be reappraised in high-risk patients such as those with wet AMD in one eye already.
The idea of using a leukemia drug for stomach cancer, an anti-seizure drug for nerve pain, a cancer drug for gout all were impactful suggestions proposed by physicians or researchers outside the company developing the drug.
The idea itself is not new--using existing molecules as a template is a hallmark of drug development.
Celsion is dedicated to the development and commercialization of oncology drugs including tumor-targeting treatments using focused heat energy in combination with heat activated drug delivery systems.
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"There were several people here at the 'Hutch' who were thinking about starting a company around using yeast in drug discovery, " says Hartwell, a calm-spoken man with a bristly gray mustache.
Doctors can break up the clot by using Activase, a drug used by Genentech (nyse: DNA - news - people ), but that drug must be used quickly after the stroke happens.
He was accused of using performance-enhancing drugs by other riders, but never failed a drug test.
Here's how Zeneca, a London-based pharmaceuticals firm, went about using Incyte to help it discover a drug that would bust bacteria without hurting humans.
The U.S. Department of Justice announced that the Atlanta-based company would also "take steps" to block illicit online drug dealers from using their delivery service.
The researchers suggest instead using a cost-benefit approach - such as how many cases of remission a drug can provide, or how many relapses it might prevent.
The drug works by using high doses of the female hormone progestin, which also is contained in birth-control pills, to block a potentially fertilized egg from becoming implanted in a woman's uterus.
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The study included patients admitted to the hospital with recently diagnosed AF in the province of Quebec, Canada, from 1998-2007, using administrative data with linkage between hospital discharge, physicians, and prescription drug claims databases.
The drug works by using high doses of the female hormone progestin, which also is contained in birth-control pills, to prevent ovulation or block a potentially fertilized egg from becoming implanted in a woman's uterus, according to the drug's label.
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Although full data is not available, two studies using the pill and an injectible version of the same drug as painkillers for patients undergoing open-heart surgery have now shown it raises the risk of new heart attacks.
His two biggest holdings are AMARIN (AMRN, 15), a volatile biotech focused on combating cardiovascular disease by using purified fish oil, and DEPOMED (DEPO, 5.5) , a drug-delivery outfit.
The big debate about the drug is whether lowering cholesterol with Zetia is as good as using a higher dose of a statin drug like Lipitor, Zocor or AstraZeneca (nyse: AZN - news - people )'s Crestor.
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