"Bukowski had a story that essentially was saying that it's the little things that drive men mad, " Waits said.

CNN: Tom Waits: The bard of Americana

The heart has its reasons, the reasons drive us mad, and his task is to forge a style from the result.

NEWYORKER: A Girl Cut in Two

Rabies hops between nerve cells as it races to the brain, which is why even an infected bite on the ankle will eventually drive someone mad.

ECONOMIST: Connectomics aims to map the atlas of the brain

Do David Robertson's high socks drive you mad?

WSJ: How to Enjoy Lousy Baseball

Of course, walking into any big-box electronics store to peer down aisles of seemingly identical flat screens could drive anyone mad before they ever step on campus, so we've narrowed down the list for you, and even suggested a few other items to plug into those HDTVs.

ENGADGET: 's back to school guide 2012: HDTV HD

Fans help, but their noise is beginning to drive us all mad.

FORBES: Chilling Out

The long winters would drive me stark-raving mad.

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Enough people are mad enough, in fact, to fuel what is becoming an irresistible tax-cutting drive.

CNN: Death And Lower Taxes