But Drescher is a sitcom veteran and knew where she stood the best chance of securing an audience.

FORBES: You're Divorced. Now Smile!

Fran Drescher is hilarious as one of the girlfriends, Joy: she combines sexy wheedling and flat-out nagging in a completely original way.

NEWYORKER: Cadillac Man

Drescher told CNN's Larry King that "senior senators on both sides of the party lines" have encouraged her to go after the seat.

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"We felt that Suzlon, which was learning to become a global supplier, was the best option for our small, community-based projects, " says David Drescher, vice president of the wind energy group at John Deere Credit.

FORBES: International

O'Donnell will play Katie O'Grady, an old high school friend of Fran (Drescher) and Judi (Tichina Arnold) who arrives to help Fran learn a lesson about her relationship with her overbearing mother Dori (Rita Moreno).

CNN: STORY HIGHLIGHTS