Ferguson made a double change on the hour, sending on Carlos Tevez and Wes Brown for Berbatov and Gary Neville.
With a trip to Manchester United looming on Saturday, Wenger made a double change with 19 minutes left, sending on Arshavin and Jack Wilshere for Eduardo and Eboue.
BBC: SPORT | Football | Europe | Arsenal 3-1 Celtic (agg 5-1)
As United held firm, with an ever-present menace on the counter-attack, Ancelotti made a double change with 20 minutes left, replacing Yuri Zhirkov and Drogba with Florent Malouda and Nicolas Anelka.
Villa boss Martin O'Neill made a double change after 52 minutes in an attempt to revive his side's hopes, sending on Shaun Maloney and Isaiah Osbourne for Gardner and Luke Moore.
But snooker legend and BBC commentator Terry Griffiths, who is one of the nine to do the snooker double, believes the change in lifestyle might have also boosted his game.
In repositioning their assets, the M100 took a marginally bullish though heavily hedged stance, pouring cash into both the iShares Lehman 10-20 Year Treasury Bond and, to a lesser degree, into Ultra Industrials ProShares, and ETF that moves at a rate double the amount of change in the Dow Jones U.S. Industrials index.
He welcomed the call to allow second trials but said it was "irrational" to confine the change in the double jeopardy rule to just murder trials.
Now Mrs Ming, who has been campaigning for a change in the Double Jeopardy law, is meeting Attorney General Lord Goldsmith and other members of the House of Lords to argue her case.
It is likely the matter will come before the Scottish Parliament early next year, and with opposition parties signalling their support for a change to the double jeopardy law it is likely to pass through easily.
There is some risk that after you have sunk your money in, Congress will double-cross you with a change in the tax laws.
Hibernian manager Colin Calderwood made a double substitution in an attempt to change the pattern of play with Ian Murray and Colin Nish withdrawn and David Wotherspoon and David Stephens sent on.
That average hides considerable variations with some clubs making double digit increases and Chelsea making no change at all.
Plans to change this policy would result in double-taxation on domestic oil and gas producers.
Nowak offers up one specific change that he figures would instantly double sales: charging for branded pages.
We also saw the largest amount of money pulled from emerging markets since the fourth quarter of 2008, according to UBS. For the first time in several months, the monthly change in foreign exchange reserves declined double digits.
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The number who said they might change their mind was in the low double digits.
The way we're going to create jobs here is not just to change our tax code, but also to double our exports.
Football At home, Le Arsenal did the Double, while the shape of the game began to change with takeover bids from City giants.
And despite Moyes' attempts to change his team's focus with a double substitution, the on-loan Sturridge again showed his ruthlessness in front of goal when he fired in to double Bolton's lead.
If we were to, for example, double the money supply but also double the quantity of goods, then there would be no price change at all.
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The tendency towards hyperbole may stem from the sense of despair among some scientists at the way climate change has disappeared from much of public discourse since the double whammy of Copenhagen and Climategate.
Lutnick convinced him to change the firm from a corporation into a partnership, to avoid double taxation.
The most important result of this sea change for the sector will mean that its decades of growth, usually in the double-digits, will be knocked down as companies reinvest and prepare to play in global markets.
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One floor higher though, things change: You get a nice view of the town and a junior suite at a double-room price.
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There was certainly a quick rebound in performance that is the norm with any managerial change, and Di Matteo did take the team on to the FA Cup and Champions League double against improbably long odds.
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Change them in yet another way and book value, the asset value, of many stocks could double or even treble.
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