At school, new rules required her to go to the nurse for each dose of medicine during the day.
That would result in computing a dose of medicine for a 100-year-old person -- possibly fatal for a child.
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Samantha Pfeifer, an associate professor of obstetrics and gynecology at the Perelman School of Medicine at the University of Pennsylvania, says the test is usually used to determine what dose of fertility medicine to use for IVF.
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Without adequately testing the drugs, doctors don't even know if they are giving children an ideal dose of a medicine.
That means the highest dose of the medicine that the company has tested, 80 mg, will probably not be approved in the near term.
Worse, one in 250 patients taking the highest dose of the medicine had serious muscle-weakening side effects, which in rare cases can be lethal.
Siga vehemently disagreed, expecting a much larger payment for a dose of the medicine based on their argument that their intellectual property was far more valuable than what the government was prepared to acknowledge.
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Some Indian analysts have also suggested that the United States take a dose of its own medicine in accepting international observers in future elections.
Once, in a lecture, a doctor Church did not know stood up and told him he needed to change the dose of his cholesterol medicine.
"It was a safe dose of a kids' medicine, with side effect of sleepiness, " he says.
Tests in animals showed that one dose of axonally delivered pain medicine could last up to four days.
After a call to the APCC, Shakespear got a daily dose for a week of human-heartburn medicine Pepcid to prevent stomach irritation from the overdose.
Just recently, a third theory has entered the arena, that Alexander died from a maladministration of hellebore, a medicine that, if given in too large a dose, could also be a toxin.
While the FDA is saying new patients should not be started on the 80-milligram dose, it is not saying that those who have been taking the medicine should switch, because the side effects are most likely in the first year of treatment.
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According to briefing documents available on the FDA's Web site, sound-alike and look-alike names are a common cause of medicine errors--when patients receive the wrong drug or the wrong dose.
Also exciting: a stop-smoking pill, a long-delayed inhaled insulin, an osteoporosis medicine, a sleep drug and an antibiotic that can treat infections in a single dose.
If you're going to administer painful medicine, then it's better to do so decisively and all in one dose than to revise and renegotiate down the road.
"You cannot give dose-dense chemotherapy without Neupogen, " says Marc Citron, a professor at Albert Einstein College of Medicine in Brookeville, N.
In one early test of the medicine, which must be injected, patients whose cholesterol was still too high on the 10-milligram dose of Lipitor had their Lipitor dose upped to 80 mg.
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