• The study, SURVIVE, compared Simdax, also known as levosimendan, with an older treatment called dobutamine.

    FORBES: Abbott Heart Failure Drug Misses Goal

  • Some doctors feel that dobutamine, the drug to which Simdax was compared, might have ill effects.

    FORBES: Abbott Heart Failure Drug Misses Goal

  • Often, doctors turn to older medicines like dobutamine and milrinone to try and improve symptoms.

    FORBES: Open Questions For Heart Failure Drugs

  • He says that he believes well-informed patients would prefer doctors look to identify an alternative to Simdax, dobutamine, or Natrecor.

    FORBES: Magazine Article

  • This may have happened with infusion clinics for heart failure drugs like dobutamine and Natrecor, where patients enjoyed the long infusion.

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  • Existing drugs such as Lasix, a water-draining diuretic, and new entries Natrecor and dobutamine haven't been tested in major trials or are suspected of serious side effects.

    FORBES: Magazine Article

  • The goal of the trial was to show that Simdax reduced mortality by 25% compared with dobutamine, which some doctors believe may actually have a negative effect on how long patients live, at the end of six months.

    FORBES: Magazine Article

  • Simdax, which is given in the hospital when patients are extremely sick, never reduced mortality by a large enough margin compared with dobutamine to be sure the results weren't due to chance, but there was a consistent trend toward a benefit.

    FORBES: Magazine Article

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