"The possibility that the drug will only do the good things like lose weight and not have myriad effects on the body -- is zero, " he said.

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There is also the risk that a pan-European supervisor could do more harm than good if such a body were overly politicised, like so many continental regulators.

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"Exercise is known to help with sleep if you don't do it just before bedtime, " possibly because it promotes overall good health and helps enhance the body's circadian rhythm, which promotes activity during the day and resting at night, says Rapoport.

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" He thinks the US president in particular could do with a makeover, "He's got a good body and he's easy going, " Frank says, "but he dresses too uptight, like a banker.

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