We doknow that when smallpox has been introduced into populations who have not encountered the virus before, such as what happened during the colonization of the U.S., that smallpox had a much higher fatality rate, certainly exceeding 50 percent.
If these genes are so important to the proper operation of the cell and we donotknow what they do, it means we still have a long way to go before we fully understand cellular life - and that includes humans.
Another way of putting this is that police constables are supposed to be experienced and sensible men and women who have both heard naughty words before and also know that while sticks and stones etc, names donot hurt.