It is a fast-growing North Atlantic salmon that contains a new Chinook salmon growth hormone gene and a DNA regulatory sequence that keeps the gene turned on all year instead of only during the warmer months, as in nature.
Professor Patrick Morrison said they would test DNA for an altered gene that can cause the body to produce too much growth hormone.
To do so, researchers at Seoul National University injected the DNA from the 11 gene donors--males and females from the ages of 2 to 56--into 185 eggs donated by 18 women.
Sangamo scientists have engineered a library of 10, 000 fingers by tinkering with the variable region, designing it so that it will seek out, recognize and bind to a specific segment of DNA for a specific gene.
Alan Trounson at Melbourne, Australia-based Monash University, a leader in the field, says that even if a cloned baby's genome was checked gene by gene with DNA microarrays such as those made by Affymetrix (nasdaq: AFFX - news - people ), there could be no assurance that the baby would be healthy.
So finding a single gene in our DNA is like finding a needle in a haystack.
Much of this proprietary DNA is involved in regulating gene activity for example, controlling how much of a protein is produced, rather than changing the nature of the protein itself.
Later, Kobilka isolated the specific gene that serves as a DNA blueprint for that adrenaline receptor.
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Three years later it isolated the BRCA1 gene, a segment of DNA that marks 600, 000 American women with a greater than one-in-two chance of developing breast cancer.
Its biologists called up two Incyte databases -- LifeSeq, with 3 million human gene fragments containing 850 million DNA xunits, and PathoSeq, with 30 bacterial genomes containing 75 million units.
These cancers are thought to result from energetic particles striking DNA, breaking strands, and interfering with gene replication.
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He has spent the last ten years trying to build them and has come up with of 70, 000 DNA parts that can be used to control gene expression.
When automated gene sequencers began sifting through thousands of DNA units a day, Incyte switched its focus to genes in 1993.
Lander and his colleagues say evolution's lab book points to only 30, 000 genes--if a gene is defined as a stretch of DNA that codes for one of the proteins from which the body is built.
Merck (nyse: MRK - news - people ), the world's third-largest drug company, is using gene expression arrays, also known as DNA chips, to keep clinical duds from reaching expensive animal or human trials.
Using automated sequencing machines from Perkin-Elmer, DeCode sequenced the DNA from the healthy and the sick to locate the gene.
Almost instantly, there was talk about a cure, about using gene therapy to fix the errant bits of DNA code and make children whole.
The fact that Millennial women are purchasing Build-A-Bear items for their pets illustrates the creativity gene that seems to be part of their DNA, says youth marketing analyst Melanie Shreffler.
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Mr Brooks considers entrepreneurship central to American culture, maybe literally a part of its DNA (thanks to all of those immigrants importing the gene that makes you get up and go).
The researchers, led by Dr George Zubenko, found that a small area of Chromosome 10 of human DNA called D10S1423, when combined with a previously identified gene APOE E4, produced the increased risk of developing the disease.
Codon Chief Danner and John Mulligan, the founder of Blue Heron, have started an industry trade organization that will prevent misuse by flagging potentially dangerous gene sequences and doing checks on researchers who request DNA transcripts.
The two companies aim to help gene researchers quickly sift through the massive amounts of DNA data and medical record information in search of crucial genetic variations that can increase the risk of everything from heart disease to diabetes.
HERC2 has no effect on eye color, but it contains an unexpressed segment of DNA that is needed for the switching on of a nearby gene called OCA2, as demonstrated by newly published work by Robert-Jan Palstra and others at Erasmus University in the Netherlands.
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Craig Venter, the brash gene-mapper, and James Watson, who discovered DNA's structure, have gotten to look straight at their entire DNA code.
The German researchers examined the body weights and DNA of 181 relatives of 25 extremely obese patients who carried the gene mutation.
Instead they decoded cow DNA in a quick and dirty way on a new type of gene decoding machine made by a company called Solexa, with which Sonstegard had been working.
All you do is send in a cheek swab with DNA on it, and a few weeks later a variety of gene data will be posted on the Web, including whether you have genes recently discovered to be associated with risk for heart attacks, macular degeneration, glaucoma, diabetes, prostate cancer, breast cancer and a variety of other diseases (see: www.decodeme.com).
Could a strand of DNA be spliced open at a precise location at the beginning of a gene?
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They sequenced all the DNA they could get from samples, looking first for variations of a gene called 16S, which is not present in humans but can be used as a fingerprint for different species of bacteria.
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