Ugandan meteorologist Khalid Muwembe says the lake, which lies on the Equator, has a distinct effect on the region's weather.

CNN: Lethal weather on 'world's most dangerous lake'

It proposed the principle that Commons decisions with a "separate and distinct effect" for England should "normally be taken only with the consent of a majority of MPs sitting for constituencies in England".

BBC: McKay Commission: Welsh MPs' role could be limited

The structure of the police is split in more ways than that: into several distinct forces, weakening the overall effect, says one criminologist.

ECONOMIST: Mexico

There is occasional misunderstanding to the effect that perjury is somehow distinct from 'obstruction of justice.

CNN: Sen. Allard's closed-door impeachment statement

It was also home to a distinct and isolated mosquito population, so the effect could be monitored closely with only a minor risk of mosquitoes from neighbouring areas contaminating the results.

BBC: The malaria parasite is spread by mosquitoes

The bottom line is that for the time being, from a regulatory perspective each biosimilar version of an approved biological product will be regarded as, in effect, a completely new and distinct drug.

FORBES: Do You Think 'Biosimilars' Will Reduce Healthcare Expenditures? Think again.