Usually after a decade or so, half of patients with this type of MS will develop secondary progressive disease where the symptoms get gradually worse and there are no or very few periods of remission.
BBC: Simple eye scan can reveal extent of Multiple Sclerosis
Rather, they conclude that "Oscar Wilde died of meningoencephalitis secondary to chronic right middle-ear disease".
BBC: Oscar Wilde 'died from ear infection'
This secondary sequence would trigger a fast-acting neuro-destructive disease that produced memory loss and, eventually, death.
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While Guinea worm disease does not usually result in death, it is associated with incapacitating pain and secondary bacterial infections.
CNN: Rare tropical disease close to eradication
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