He eliminated 24 departments and their chiefs, each focusing on a different disease group, and replaced the rigid hierarchy with small, interdisciplinary teams of two dozen biologists and chemists who report directly to lab heads.
Cystic Fibrosis Foundation, the disease advocacy group that funded the early work on Kalydeco, had always intended to find a way to make the medicine work in patients whose disease was caused by other genes.
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They identified a previously unrecorded species of Candidatus, a group of disease-causing bacteria that infect many sorts of plant.
The Lyme Disease Association, a group that supports Jemsek, says that 30 chronic Lyme doctors have been similarly targeted by medical boards.
It wouldn't be doing so were it not for the Cure Huntington's Disease Initiative, a group that in 2004 turned itself into a biotech called CHDI.
Twenty had relapsing remitting MS, 15 had secondary progressive MS, and five had primary progressive MS. Researchers also recruited 15 healthy control patients free from ophthalmological or neurological disease as a comparison group.
The group analysed more than 29, 000 cases of children with cancer against a comparable group without the disease.
The experts have worked out that many of the extra cases are a sub-group of the disease called "pre-cursor B-cell".
To fall into the group with cardiovascular disease you need to have symptoms such as angina (heart pain), and clogged arteries diagnosed following tests.
But when the researchers reanalyzed the study looking just at those patients with normal kras, they found that in this group Erbitux delayed the disease progression by a much more robust 32%.
The idea is that when a critical proportion of a group is immune to a disease, too few individuals are susceptible for that disease to be passed from one to another.
Because of the data already being collected about these people, the study allowed Saczynski's group to control for heart disease, heart attack, stroke, smoking, alcohol use and other factors that could have influenced dementia.
They therefore predict that patterns of behaviour which promote group exclusivity will be stronger in disease-ridden areas.
Overall, a quarter with advanced cancer said they had worked night shifts, compared with a third of those with borderline disease and one in five of the control group.
Dr. Anthony Fiore of the Centers for Disease Control and Prevention, who led the group's deliberations, said it made sense to target such a large group because it appears that vaccine supplies will be sufficient.
They also saw enhanced learning and memory skills in these patients and in a group of people with Alzheimer's disease that they tested.
That's the conclusion of a group of researchers from the Centers for Disease Control (CDC), who collected water samples from 161 filters in public and private swimming pools, as well as water parks in Atlanta last summer.
"There is a group of children with severe congenital heart disease who need to arrive at hospital in good time to get treatment, and if they do so then their survival rate is very good, " he said.
Rankin and her team focused on a a specific type of neurodegenerative disease called frontotemporal dementia, or FTD, a group of disorders in which patients can experience behavioral symptoms such as personality changes, a loss of inhibition and social tact as well as language difficulties, such as an inability to understand words.
Even after making these adjustments, however, the olive-oil group showed statistically significant drops in heart-disease risk.
Six percent of the men and four percent of the women regularly used NSAIDs, and from this group, 415 cases of Parkinson's disease were diagnosed.
That group had isolated the gene for Huntington's disease in 1983, which paved the way for the human genome project.
Dr Dai Lloyd AM who chairs the cross party group said he was "shocked" that muscle disease patients and their families had to "put up with such poor healthcare in Wales".
At that point the HRT-takers stopped taking hormones, and the researchers analyzed the results, finding that half as many women in the HRT group had had heart problems or died of heart disease than non-HRT takers.
Trained dogs were asked to sniff out a study group that included lung cancer patients, chronic obstructive pulmonary disease (COPD) patients, and healthy volunteers.
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The Meningitis Trust was formed in 1985 after a group of parents got together following an outbreak of the disease in Stroud and Stonehouse.
The first group involved eight older monkeys with early Parkinson's disease.
Dr Amerson's group has found markers that distinguish fungus-resistant stock from disease-prone trees.
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The second group were injected with a chemical to cause Parkinson's disease.
The study didn't find any difference in disease progression a year after treatment between those taking lithium and the control group, researchers said.
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