You may not be in as heated a crucible or as devastating a trust void as Armstrong, and therefore the importance of trust may not seem as obvious.
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But at some point he noticed that returning to reality from the world of a novel was not as devastating a blow as returning from the world of math.
From an economic standpoint, losing a job is devastating to a lot of families.
This means that big exchange-rate movements can have a devastating impact on a country's balance sheet.
Pancreatic cancer is a devastating disease with a five-year survival rate of 5.5%.
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An estimated 80 percent of livestock here have died in the drought, a devastating loss for a society of subsistence farmers.
Secretary of State for Work and Pensions Iain Duncan Smith said family breakdowns could have a devastating effect on a child's life.
Racked by decades of violence, Colombia today faces a devastating assault from a powerful, well-financed guerrilla group calling itself the Revolutionary Armed Forces of Colombia (FARC).
Even after a lull in winter, they'd wake up in the spring in greater numbers and, without action, remain a devastating presence for a full decade, Huynh said.
Carter said the budget reductions would have a devastating effect on a number of Pentagon programs, but continued investment in offensive and defense cyber operations would continue, along with unmanned systems, space capabilities and electronic warfare.
"Sandy was a big storm that was devastating to a lot of people, " he said.
"Sandy was a big storm that was devastating to a lot of people, " the mayor said.
Then, in March, Japan was hit by a devastating earthquake that triggered a tsunami and, ultimately, a nuclear disaster.
For most investors the Japan story is the definition of ugly: a devastating tsunami followed by a nuclear reactor meltdown.
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In 2006 a devastating mudflow erupted near a site in Java where Lapindo Brantas, a Bakrie-controlled company, was drilling for gas.
That would be a devastating indictment of any kind of business, but it is probably most devastating of all at a bank.
The sudden Congressional decisions to ditch the very bad intellectual property bills, the Stop Online Piracy Act (SOPA) and Protect Intellectual Property Act (PIPA) have raised all sorts of new questions about how discussion around the bills should proceed and, as importantly, how was it the opposition managed to have such a devastating impact on such a powerful lobby as the movie studios and their friends.
It doesn't take much imagination from even a brief visit--which I made a month before the cyclone struck--to see how devastating such a storm would be.
We've lost a lot of one-run games, and those can be devastating to a team.
Towards the end of the fifth round, the 31-year old unleashed a devastating left-hook before a follow-up right hand floored Chisora.
There was a young woman with multiple organ failure from a devastating case of pneumonia, a man in his mid-sixties with a ruptured colon that had caused a rampaging infection and a heart attack.
What the injury proves for certain though is that professional football is a brutal sport where a promising career can come to a crashing halt because of a devastating injury caused by even a moment of indecision.
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He traces the entire history of the company and shows how the unconventional thinking championed by Mori will be vital as Japan faces the challenges of recovering from a devastating tsunami while dealing with a shrinking population and a turbulent global economy.
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Health insurers, fearing that they could be squeezed out under the new system, broadcast a devastating television commercial that featured a suburban couple, Harry and Louise, expressing their confusion about the plan and their worry that the government would make health care decisions.
He also said that the income losses engendered by the banks was as devastating as a world war.
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There is nothing more devastating than a good business that fails to launch.
And SBY won high marks for the vigorous way in which he responded to the devastating tsunami a year ago.
"This utterly unacceptable escalation of the conflict could lead to a devastating loss of civilian life and a humanitarian disaster, " he said.
He noted that Napster's defense on these grounds would likely only stand if the company could show that the effect of altering the technology would be devastating to a large segment of society.
Japanese industries would suffer a devastating blow were Japan not to be a party to this agreement.
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