Todd Akin and Richard Mourdock self-destructed last fall, and other candidates squandered important opportunities.
There are numerous cases of accomplished people who inherited money in their 30s and 40s and nevertheless self-destructed.
McIlroy, looking confident, held a four-stroke lead heading into Sunday's final round but self-destructed on the back nine.
When former CEO Brian Dunn self destructed in early 2012, Schulze was caught in the crossfire and resigned as chairman.
In doing our homework, my wife and I learned of accomplished people who inherited money in their 30s and 40s and nevertheless self-destructed.
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Barca then self-destructed as Ludovic Giuly and Gianluca Zambrotta saw red.
Tomorrow may be built on the conventional paths of small business, but will be creatively destructed to emerge as radical agents of change just the same.
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Two younger hopefuls, Bobby Jindal (governor of Louisiana) and Mark Sanford (governor of South Carolina) have self-destructed, one with a dismal speech, the other with a sexual scandal.
If George Allen, who had a gigantic lead three months ago going into this race - had he not self-destructed, I think George Allen would be still in the Senate.
Mitt Romney became the Republican nominee because Herman Cain, the only true pro-growth candidate in the primary race that was actually competent to do the job of president, self-destructed over personal issues.
As Mickelson and Johnson self-destructed, Clarke strolled to a relatively easy three-stroke victory, becoming the third different golfer from tiny Northern Ireland to win majors in the last 13 months, extending the American majors drought to six.
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Gillingham, without a win on their travels in 17 months, were back level when McDonald raced half the length of the pitch to chip over keeper Ian Dunbavin, but they self destructed when they conceded two penalties in four minutes.
Miyazato, who briefly shared the lead on one under par, also self-destructed with a double bogey on 17, while Matthew's closest overnight rival, Kim, haemorrhaged shots early on and despite knocking in a couple of birdie putts, was never in contention.
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