Although bupropion isn't generally considered a first line treatment for depression during pregnancy, it might be an option for women who haven't responded to other medications or those who want to use it for smoking cessation as well.

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The number of prescriptions for anti-depressants hit a record high of more than 31 million in England in 2006 - even though official guidance stresses they should not be a first line treatment for mild depression.

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Bottom line: one can argue whether depression is physical, mental or both.

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Mr. LAITHUM: I'm thinking maybe something along the line of what they did during the Depression, when they made the Public Works program where the government put people to work.

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The next step in this line of research is to examine brain images to see what roles depression and dementia may play in the brain, and better understand the mechanisms behind the connection between these two disorders, Saczynski said.

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The Great Depression and the wave of regulations that came out of the crisis undid this philanthropic line of defense.

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