Occasionally the threat lay in that buzzword of today, globalisation, and its concomitant demand for greater scale: Chrysler merged with Daimler-Benz because, even as number three in the world's largest car market, it was too small to prosper alone.
The demand for larger-scale private and corporate jets has been such that the major aircraft manufacturers, Airbus and Boeing, now offer modified versions of their passenger aircraft -- the Boeing BBJ (Boeing Business Jet) and Airbus CJ (Corporate Jet).
The price of anything has three components: supply, demand and the scale used for measurement.
Jobs and Apple have done an amazing job of creating wealth for the U.S. Apple has created new demand for products on a huge scale (new work).
Demand for 3G-capable smartphones continued to scale up as the carrier saw more than 90% of its net adds come from 3G.
If we allowed the nonprofit sector to build the kind of demand for philanthropy that Hollywood builds for movies, we would be on our way to the necessary scale.
Large scale immigration would inevitably entrain a demand for some degree of multiculturalism.
Its union with Freeport, it said, would benefit from strong global demand for copper, alongside a scarcity of large-scale copper development projects.
It might be able to demand 6% royalties or more for something ready for large-scale trials, versus half that for a totally unproven treatment.
With the scale heavily weighted to demand, it was not for nothing that new-issue clearing yields fell significantly in January, reaching new credit-crunch lows.
The scale of the Chinese demand is going to create substantial opportunity for gold investors.
On the one side, they can get a guarantee demand for their products, getting rid of excess capacity, and attaining economies of scale.
He said the government was wrong to blame the eurozone crisis for slow growth - it was the "scale of shrinking domestic demand" that was holding growth back.
BBC: Ed Miliband: Cuts plan has locked UK into vicious cycle
The alliance's manifesto calls for measures to reduce demand on the main electricity transmission grid, including smart meters, encouragement for community and small-scale local energy generation, and further research on methods of storage of electricity.
To meet the growing demand for the Model T, he designed the first moving assembly process to produce cars on a large scale.
For manufacturers struggling to find the right balance between supply and demand, business networks provide much needed visibility, scale and efficiency.
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