What if a serious form of asthma or heart condition is discovered that could cause sudden death or stroke under the extreme conditions of professional competition?
FORBES: Is The NFL Going To Test Players For Genetic Defects?
According to a press release issued to reporters, 13.2% of the patients receiving Tredaptive had a heart attack, heart-related death, stroke, or need for a stent procedure or bypass surgery.
Lilly's own studies show that Zyprexa doubles the risk of stroke death when given to elderly dementia patients.
With death rates from stroke declining, it's increasingly important to find new treatments to help survivors make their best possible recovery.
The primary endpoint was the time to first major vascular event, defined as the composite of non-fatal MI or coronary death, any stroke or any arterial revascularization.
News that Hosni Mubarak, ousted last year after 30 years as despot, was near to death after a stroke in prison may be irrelevant to the outcome of the current power struggle.
Of the patients who received chelation, 27% had one of the following: a death, a stroke, a heart attack, a stent procedure to open a heart artery, or a hospitalization for chest pain.
FORBES: Doctors Dismiss Study That Says Chelation Helps Heart Patients
But Ta Mok's death and a stroke just suffered by Khieu Samphan, once the Khmers Rouges' head of state, is a poignant reminder that justice is more than ever a race against time.
But AtheroGenics claims that the trial actually shows a statistically significant benefit in preventing the combination of heart attack, stroke and death.
Many researchers, however, point out that the 30-day stroke and death rate in stent patients was significantly higher (4.8%) than that of surgery patients (2.6%).
At the end of the study, 3.8% of the Mediterranean-diet-plus-olive-oil and 3.4% of the Mediterranean-diet-plus-nuts groups suffered a heart attack, stroke or death from cardiovascular disease.
WSJ: Mediterranean Diet of Olive Oil, Nuts, Reduces Heart Disease, Study Finds
If the AGI-1067 study results are convincing, it could still eventually become the first truly new medicine introduced in a decade to reduce heart attacks, stroke and death.
When Topol co-authored an influential paper on Vioxx and Celebrex in 2001, he and his colleagues looked at three certain signs of cardiovascular risk: heart attack, stroke and death.
Researchers found that participants taking Crestor cut their risk of heart attack, stroke and death by nearly half -- 44 percent -- compared with participants taking the placebo.
CNN: Study: Cholesterol drugs could help those with healthy levels
The label now includes a black box warning that it can increase the risk of death, MI, stroke, venous thromboembolism, thrombosis of vascular access, and tumor progression or recurrence.
FORBES: Amgen Pleads Guilty To Misbranding Anemia Drug Aranesp
If AtheroGenics had set heart attack, stroke and death as the main goal of its study, these results could lead to approval by the U.S. Food and Drug Administration.
Moreover, there are additional factors buttressing a need for caution: Two retrospective analyses of Medicare claims both found increased risks of stroke and death among patients using Avastin for wet AMD over Lucentis.
FORBES: Blinded By Savings? Is Cost Trumping Risk On Blindness Drug?
It is supposed to be much more difficult to show a benefit in the "hard events"--heart attack, stroke and death--than in the broader swath of "extra" heart problems that AtheroGenics measured in its trial.
In a new analysis published online in the Journal of the American Medical Association, Steven Nissen and Eric Topol of the Cleveland Clinic write that Pargluva doubles the risk of heart attack, stroke and death.
The 6, 000-patient study was designed to show that AtheroGenics' drug, known by the code name AGI-1067, decreased the risk not only of heart attack, stroke and death but also of less important heart problems, including stent procedures, bypass surgery and chest pain.
The UK has one of the highest death rates from CHD and stroke in Europe.
The trial showed that patients randomized to chelation therapy had a lower risk of a combined endpoint of death, heart attack, stroke, percutaneous coronary intervention, bypass surgery or hospitalization for angina than those who received a placebo infusion.
FORBES: Researchers Who Ran Controversial Chelation Trial Respond to Questions
After 4.8 years of follow-up a primary endpoint event (the composite of MI, stroke, and death from CV causes) occurred in 3.8% of patients in the Mediterranean diet extra-virgin olive oil group, 3.4% in the Mediterranean diet with nuts group, and 4.4% of patients in the control group.
FORBES: Large Trial Shows Cardiovascular Benefits Of Mediterranean Diet
"There was a 44 percent reduction in death, heart attack, and stroke among people taking Crestor, " says Nissen.
CNN: FDA considers statin use for those with normal cholesterol
Tributes to her achievements poured in from around the globe, as well as from many in Britain, after the news of her death on April 8 from a stroke, aged 87.
Obuchi's stroke in April and death on May 14 caused an outpouring of sympathy for him (more than he enjoyed while alive), but none of it is rubbing off on his successor.
The team of researchers, led by Dr Anastasis Stephanou, carried out laboratory tests on heart cells which found that a major chemical component of green tea known as epigallocatechin-3-gallate (EGCG) can reduce cell death after a heart attack or stroke.
Those who consumed the least salt had a 56 percent higher risk of death from a heart attack or stroke compared with those who had the highest consumption, even after controlling for obesity, cholesterol, smoking, diabetes, and other risk factors.
She did not die of a heart attack but of a stroke, according to the death certificate signed by her personal physician.
During that time, 15% of patients taking Vytorin and 18% of patients in the control group had a heart attack, stroke, stent procedure, or death from cardiac causes.
应用推荐