Damien Johnson delivered a perfect chip to the back post and Healy headed home.
Chris Baird, Grant McCann, Damien Johnson, Steve Davis and McGinn will form a five-man midfield.
Damien Johnson, who starts at right-back, will captain the side while David Healy is a lone striker.
The Northern Ireland boss also lauded the performance of the experienced Damien Johnson in an unfamiliar full-back role.
Elyaniv Barda equalised eight minutes later with a close-range finish before Damien Johnson cleared Tamir Cohen's header off the line.
Damien Johnson headed over before Martin Skrtel's slip let in Paterson but Mucha rushed out to block the forward's strike.
Only captain Damien Johnson, Grant McCann and Healy had made it into double figures in appearances for their national team.
Damien Johnson, Kyle Lafferty and Grant McCann are being tipped to play in midfield with Martin Paterson partnering David Healy up front.
David Healy, Damien Johnson and Grant McCann provide the experience in the panel and Worthington expects his senior players to help the newcomers.
Steve Davis, Grant McCann, Sammy Clingan and Damien Johnson is the likely combination in midfield, with Kyle Lafferty set to partner David Healy in attack.
Bruce is already without Blues captain Damien Johnson (hamstring), but striker Mikael Forssell (head) and Stuart Parnaby (knock) are both expected to recover in time.
The NI boss added that his side were "disappointed to lose" and claimed that Damien Johnson was unlucky to be sent-off in the second half.
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Worthington made two half-time changes with Crewe's Michael O'Connor coming on for his debut in place of Damien Johnson and Lafferty making way for Warren Feeney.
Damien Johnson, Grant McCann and David Healy are the only regular senior players included as several of the first-choice squad members are unavailable because of holiday commitments.
Soon after, a purposeful Birmingham counter-attack ended with Friedel desperately having to scoop away Damien Johnson's shot after a Dunn cross created pandemonium in the Blackburn defence.
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Steve Bruce's team dominated the early exchanges, fashioning an excellent opportunity when Stan Lazaridis slid the ball through to Damien Johnson, but the midfielder could only drag his shot past the far post.
Maik Taylor (Fulham), Roy Carroll (Wigan), Aaron Hughes (Newcastle), Mark Williams (Watford), Danny Griffin (St Johnstone), Ian Nolan (Sheffield Wednesday), Colin Murdock (Preston), Pat McGibbon (Wigan), Kevin Horlock (Manchester City), Keith Gillespie (Blackburn), Damien Johnson (Blackburn), Michael Hughes (Wimbledon), Jim Magilton (Ipswich), Jeff Whitley (Manchester City), Danny Sonner (Sheffield Wednesday), Steve Lomas (West Ham), James Quinn (West Brom), Adrian Coote (Norwich), David Healy (Manchester United), Stephen Robinson (Bournemouth).
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Damien Duff burst through on the right to cross for Andrew Johnson lurking in the six-yard box and only a timely interception by Luiz guided the ball high and over the bar.
Johnson later departed following a hefty challenge from Dmitry Belorukov but Fulham remained on top and new signing Damien Duff helped his side to their third.
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