"These are very high-force, high-impact injuries so they cause a lot of damage to tissue and to bone, " said Ron Walls, chairman of the department of emergency medicine at Brigham and Women's Hospital.
The method also overcomes limitations posed by current treatments in which radiation may damage portions of healthy brain tissue.
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The concern, though not explicitly proven, is that products with higher osmolality might poses more of a risk of tissue damage.
The researchers said the early introduction of the cells might even interrupt the typical "chain reaction" of tissue damage which follows a stroke, in which the initial injury harms additional cells in surrounding areas.
There is also a significant risk of damage to the heart, which is made of muscle tissue.
Although nitric oxide did not reduce the risk of all neurologic complications, only 12% of the infants who received it suffered a severe brain haemorrhage or tissue damage, compared to 24% of those who did not.
"If they stood on one leg consistently, they would risk greater loss of body heat and potential tissue damage in the cold, " says Anderson.
Professor Petot said it was possible that when fat was broken down by the body it released substances known as free radicals that can cause tissue damage, and might precipitate the development of Alzheimer's symptoms.
But too much TNF over long periods of time is toxic, causing severe inflammation and tissue damage.
But Dr Susanne Ludgate, clinical director of the MHRA, says they had first become aware in 2008 of a small number of cases where patients suffered swelling around the hip and tissue damage.
The delayed product is designed to help patients who suffer from a deficiency of "AAT", a substance which protects the lungs from tissue damage which causes emphysema.
The retinal nerve fiber layer is the one part of the brain where nerve cells are not covered with the fat and protein sheathing called myelin, making this assessment specific for nerve damage as opposed to brain MRI changes, which reflect an array of different types of tissue processes in the brain.
Many of the injuries were to "lower extremities" and included tissue and bone damage, he said.
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This could lead to tissue damage in the artery walls, creating the potential for inflammation and the formation of life-threatening clots.
The problem of lipid damage, they believe, is linked to hormones produced not by the pancreas, but by adipose tissue itself.
Caspase-blockers may limit collateral tissue damage from strokes, heart attacks or liver disease, and Vertex hopes to begin human trials of at least one compound next year.
These iPS cells, like stem cells derived from embryos, can be turned into many different kinds of cells, and researchers believe they eventually could be used to regenerate tissue for organs and repair damage.
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