They blocked the D2 receptor just enough to alleviate psychoses without obliterating the patient.

FORBES: Silencing the Voices

For example, a genetic database created by Spectra Biomedical, a division of Glaxo Wellcome, found an unexpected correlation between migraine attacks, serious depression and variations in the dopamine D2 receptor (a molecule that sticks out of certain nerve cells).

FORBES: Tailor-made drugs

This receptor, the D2, has a counterpart, the D2 neurotransmitter, and the pairs are scattered in different command centers of the brain.

FORBES: Silencing the Voices

Both Steve Nissen and Allen Taylor say little is known about the long-term effects of its flushing-blocker, which works by blocking a cell receptor called prostaglandin D2.

FORBES: Magazine Article