Polls had suggested that Mr Castle had a better chance of defeating Mr Coons in November's general election.
Lindsey Graham, R-South Carolina, and Richard Durbin, D-Illinois, as well as Coons, Isakson and Landrieu, co-sponsored the measure.
CNN: Senators invite Americans to sign anti-Kony legislation
She will now compete in Delaware against Chris Coons, the Democratic candidate for a Senate seat formerly held by Vice-President Joe Biden.
Chris Coons of Delaware, is hosting a fundraiser for him in Washington next week, as will former White House counsel, Greg Craig.
The opinions expressed in this commentary are solely those of Chris Coons.
Mr Coons is chairman of the Senate Foreign Relations African affairs sub-committee.
Christopher Coons, D-Delaware, chairman of the Senate Foreign Relations subcommittee on Africa.
In Delaware rumour has it that party executives will resign and may even endorse Chris Coons, the Democratic candidate for the Senate seat.
Both Coons and Landrieu, who wore a red lapel pin reading "Joseph Kony 2012, " said their own daughters had asked them about Kony.
CNN: Senators invite Americans to sign anti-Kony legislation
Coons' subcommittee plans a hearing on Tuesday, April 24, to discuss ongoing efforts to help communities affected by Kony and to capture him.
CNN: Senators invite Americans to sign anti-Kony legislation
"I had a nightmare last night that I forget my voter registration card, " said Marnie Coons, a 19-year-old UVA student and Obama supporter.
WSJ: At Campuses, Obama Camp Helps Young Voters Get to Polls
While only portions of the bill became law, the partnership with Mr. Coons led the two to cooperate on four other bills last year.
Christopher Coons of Delaware and Amy Klobuchar of Minnesota, the Senate visa measure is expected to be folded into broader immigration efforts gathering steam in Washington.
Coons said it was the group's hope that the video would get 100 million views -- a reference to the popularity of the "Invisible Children" video.
CNN: Senators invite Americans to sign anti-Kony legislation
More noteworthy are the six Keystone converts, which include South Dakota's Tim Johnson, Virginia's Mark Warner, Colorado's Michael Bennet, Florida's Bill Nelson and Delaware's Chris Coons and Tom Carper.
One example of such reform is the bipartisan Immigration Innovation Act introduced on January 29 by Senators Orrin Hatch (R-Utah), Amy Klobuchar (D-Minn.), Marco Rubio (R-Fla.) and Chris Coons (D-Del.).
FORBES: Want To Reduce Income Inequality? Lower The Barriers To Talented Immigrants
Coons said the Rewards for Justice Program had been successful in helping to motivate people to give information in the search for Moammar Gadhafi, Saddam Hussein and Osama bin Laden.
CNN: Senators invite Americans to sign anti-Kony legislation
When he holds fundraiser for Coons on Friday and Patrick on Saturday, he goes to Cleveland in Columbus, are you telling us this will be a major part of his address?
The Startup Act 2.0 originated by Senator Jerry Moran (R-Kan.) and Mark Warner (D-Va.) and now joined by Chris Coons (D-Del.) and Marco Rubio (R-Fla.) will be the hot topic Jan. 2013.
The SMART Act, introduced by Lamar Alexander (R-TN) and Chris Coons (D-DE), is better because it would create a new temporary visa for STEM graduates without eliminating any other green card categories.
FORBES: Positive New Steps To Reform High-Skilled Immigration
Mr. Coons and other police officials want the money restored, noting that so-called lone-wolf attacks are occurring more frequently outside of major urban areas, such as the movie theater shootings in Aurora, Colo.
"I have been very surprised by Marco's willingness to take political risks by working with me on things that are hard to describe in narrow ideological terms, " Mr. Coons said in an interview.
"The issue is that we'll have to look within and see where we could find funding to sustain our programs, " said Gary Coons, chief of the Division of Homeland Security in the Indianapolis Department of Public Safety.
"There are folks who are currently in the LRA who we are trying to ... encourage to leave the LRA and this might provide some additional incentive both for current or former LRA fighters to leave" and "provide critical recent intelligence about their movements, their practices and Kony's recent whereabouts, " Coons said, adding that providing this kind of information often means risking their lives.
CNN: Senators invite Americans to sign anti-Kony legislation
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