The salts from succinic acid are also effective in coolants and are less toxic than other cooling chemicals.

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The UK government is currently aiming to phase out the use of PCBs as coolants and lubricants in industry.

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Once a patient's heartbeat is restored, emergency-room doctors, cardiologists and rescue squads are quickly applying ice and other coolants to moderately lower a patient's body temperature by about six degrees.

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In 1928, Thomas Midgley, Albert Henne, and Robert McNary synthesized the first chlorofluorocarbons (trademarked as Freon in 1930), ushering in safe refrigerators and air conditioning (other coolants eventually replaced Freon).

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