He has managed to reprogram mouse connective-tissue cells so that they develop into cardiac muscle cells, and has tested them in the hearts of mice that have had heart attacks.
Fast-forward a couple more years and Deepak Srivastava, a scientist at the Gladstone Institute in San Francisco, found his own three-gene recipe for turning the plentiful, plebian cells that form connective tissue in the heart directly into cardiomyocytes, the cells that make the heart beat and are damaged by heart attacks.