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An on-board computer gets the machine's position from satellites and reads a digital blueprint from a chip.
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In the same way, knowing the activity of every wire on every chip in my computer wouldn't tell me much if I didn't also know the program my machine was running.
WSJ: How the Brain Really Works | Mind & Matter by Alison Gopnik
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At the heart of the personal genome machine is a silicon chip with 21 million transistors on it--the equivalent of a desktop computer circa 1995.
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