When coffee beans are roasted, the plant compound, chlorogenic acid, is broken down.

NEWYORKER: The Operator

But the only firm that achieved any success was Novartis, which in 1998 developed Coartem, an antimalarial drug that combines artemisinin, an extract from the sweet wormwood plant, with a compound called lumefantrine.

FORBES: Magazine Article

They contain a cyanide compound, a natural part of the plant's defense mechanism.

NPR: Falling in Love with Limas