The second motion, also agreed, expressed concern over the management's understanding of clinical needs at the hospital.

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But that system was heavily criticised because some patients with higher clinical needs ended up waiting longer because hospitals were trying to meet government targets.

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"The current trial designs may not optimally meet the scientific needs of prescribers, the clinical needs of patients, the economic needs of payers or the regulatory needs of policymakers, " Avorn wrote.

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"Not all will do so and to that extent of course I make it clear that the NHS is there to support women in their clinical needs whatever their other circumstances may be, " he told MPs.

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Even with the current guidelines, Al-Khatib said, some patients may fall into a gray zone and that each physician needs to use clinical judgment to make recommendations.

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In a press release, Dendreon said that the FDA wants more data from clinical trials, but that the company needs clarification on exactly what it needs to do.

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"ImClone needs to do the right clinical trials, " Mooney says.

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Isis needs one in order to start a large and expensive clinical trial testing its drug in patients who have high cholesterol that is not caused by a genetic defect.

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The manufacturers have hard on a slew of lobbyists to convince Congress that the Medicare payment rule needs to be changed back so that doctors can use their clinical judgment for that mid-level anemia.

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Nonetheless, Berry says that most companies are "making solid progress" in development and clinical trials and that Big Pharma, with pipelines running dry and blockbuster drugs coming off-patent, needs biotech partners more than ever.

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