In general terms, a change in your genome sequence can mean a small alteration, like removing or adding a single link in a chain, or it can mean a structural change involving bigger chunks, like removing or adding whole sections of the chain.

FORBES: Autism And Genetics: It's Complicated

But when the virus produces protein, a troublesome mutation results in a change to the amino acid sequence that makes up the protein.

ECONOMIST: Viruses: Hunt the mutant | The

Wages and salaries data for February pointed to no change in permanent salaries since January, ending a four-month sequence of increases.

BBC: Fall in Scottish permanent job placements