The things we have shared and the challenges we have faced together as football players, choral students, colleagues and friends give me the strength to move forward and meet this latest challenge in my life with a firm resolve.
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Sir Paul believes strongly that scientists have a duty to speak out about science in public life and challenge pseudoscience.
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Allowing those convicted of serious crimes in England and Wales to challenge their life-long duty to notify police of their whereabouts may be controversial, but ministers insist they have little choice.
Another is to get disabled people from other walks of life to come in and challenge preconceptions about disability.
But we need leaders in business and public life who challenge us do what we thought was impossible, who stir our souls, captivate our imaginations, and elicit the kind of bravery Armstrong showed when he took those first magnificent steps.
The spokesman said it would be open to any offender serving a sentence in the community on life licence to challenge a particular licence condition.
At bottom, however, all have a healthy tolerance for risk, an addiction to change and challenge, and strong views on what matters most in life.
If you haven't thought about it, I leave you with this challenge: Serve a neighbor in need, because a life of service is a life of significance.
But after five months out of the game following a scandal in his private life, the 34-year-old could not sustain the challenge and instead made six bogeys in his first 12 holes.
The biggest challenge facing the system was the "significant increase" in life expectancy, she told MPs, as she opened a backbench business debate on the matter on 8 March 2012.
And like anything else in life, one has to see it as a challenge.
While a challenge, balance, in general, is something I strive for in my life.
It's a challenge even in Miami, where speaking Spanish is practically a requirement for everyday life.
Mohammad Azharuddin has begun a legal challenge to the life ban imposed on him by the Board of Control for Cricket in India over match-fixing allegations.
But now, in the later innings of his life, he must rise to an unseemly challenge: to salvage his reputation and his fortune, Wilpon must prove that he was a dupe rather than a crook.
At Miraval, Life in Balance, guests are invited to try any number of "challenge" activities--balancing a feather on the palm of the hand, climbing (while tethered) the 25-foot Quantum Leap pole and then jumping off, learning to approach a horse and pick up its hooves.
Developing a substance that would work reliably in potentially extreme conditions and remain stable over the life of the material was also a challenge.
The Ocean Challenge Badge is designed to help educate children and young people about the vital role the ocean plays in supporting life on Earth.
There are times in the history of our nation when our very way of life depends upon awakening to the challenge of a present danger, shaking off complacency and rising, clear-eyed and alert, to the necessity of embracing change.
However, even for individuals with the means and desire to give as much as possible, the challenge is always to give in a manner or up to the point that does not jeopardize liquidity and lifestyle through life expectancy.
But just as people in countries across the region are busy contesting received wisdoms in politics, and are starting to challenge the role of religion in public policy, I hope they will start asking the same hard questions of sexual life.
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