For a T cell to become active, it must receive signals from another part of the immune system called an antigen-presenting cell.
ECONOMIST: Breaching the body's defences
However, before the alarm can be sounded in this way, proteins on the surface of the antigen-presenting cell and the T cell must bind together in what is called a cellular handshake.
Out of tens of thousands of proteins in a cancer cell, less than one in a thousand may become a cancer antigen.
FORBES: In search of antigens
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