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It was hoped that by hitting EGFR, the out-of-control cell division that marks cancer cells could be stopped--making chemotherapy more effective.
FORBES: Why Cancer Drugs Need Genetic Testing
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The Detroit News and Detroit Free Press both reported Friday that GM is moving the engineers -- who have been working on the fuel-cell technology in the company's advanced development laboratories division -- to the company's core production engineering division, which designs vehicles to be brought into production.
CNN: GM takes step toward fuel-cell car
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Due to its strong patent position, it also collects fees from 195 licensees, spanning most of the cell-phone industry for code-division, multiple-access technology, which is the standard communications technology in cellular networks.
FORBES: Connect
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In both cases, he used the heavy-water method to monitor cell division.
ECONOMIST: Longevity
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Some corneal cells rarely, if ever, reproduce through the course of a lifetime, and inducing cell division could result in a cancer-like condition of uncontrolled growth.
BBC: Human cornea grown in lab
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The drug works by inhibiting an enzyme called the proteasome, stopping the normal progression of cell division and causing cancer cells to self-destruct.
FORBES: Magazine Article
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It's a variation on the well-established breast cancer drug Taxol, which works by inhibiting cell division.
FORBES: Patrick Soon-Shiong and one of cancer's biggest riddles.