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When the CDX-011 antibody attaches to GPNMB-expressing tumor cells, it releases a toxic chemotherapy payload.
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The vaccine, based on research done at Duke and Johns Hopkins, and produced by Pfizer, is called CDX-110.
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CDX-110 is not the only candidate for a brain cancer vaccine, either.
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The research with CDX-110 is further along, but results from the first multicenter trial will not be made public until later this spring.
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Thirty-two percent of those 25 women (that would be 8 people) had a response, compared to 13% of the 8 high-GPNMB patients who did not get CDX-011.
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The new CDX-GS500R CD receiver features Sony's new App Remote technology for iPhone, while the new CDX-GT710HD model includes HD radio technology and a dynamic color illuminator for different light effects.
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Other notes: CDX-011 is a monoclonal antibody drug conjugate.
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The results in that small group could allow Celldex to design a future trial that could, on its own, lead to accelerated approval with the Food and Drug Administration for the drug, known as CDX-011 or glembatumumab vedotin.
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