Cubist Pharmaceuticals Inc. ( NASD: CBST) is up about 1.4%, and ProAssurance Corp. ( NYSE: PRA) is up by about 0.3%.

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Cubist Pharmaceuticals (nasdaq: CBST - news - people ) now sells Cubicin, a first-in-class injectable bacteria killer it licensed from Lilly.

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"They have the sheer power of simple mutations, " says Francis Tally, chief scientist at Cubist Pharmaceuticals (nasdaq: CBST - news - people ) in Lexington, Mass.

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Among the largest underlying components of PSCH, in trading today Salix Pharmaceuticals Ltd ( SLXP) is off about 2%, and Cubist Pharmaceuticals Incorporated ( CBST) is lower by about 1.6%.

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Cubist (nasdaq: CBST - news - people ) chief executive Michael Bonney says it is not part of Cubist's plan to sell to a larger pharmaceutical company.

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On the same day that Encysive got its bad news, Cubist Pharmaceuticals (nasdaq: CBST - news - people ) announced a two-month delay on a key new marketing claim for its antibiotic.

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In a Sept. 23 note to investors, Merrill Lynch analyst David W. Munno, who covers antibiotic maker Cubist (nasdaq: CBST - news - people ), a Vicuron competitor, wrote that he suspected Pfizer had received an approvable letter.

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Among the largest underlying components of XBI, in trading today Seattle Genetics Incorporated ( NASD: SGEN) is down about 1.4%, Alexion Pharmaceuticals Incorporated ( NASD: ALXN) is off about 0.8%, and Cubist Pharmaceuticals Incorporated ( NASD: CBST) is lower by about 0.5%.

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In 1995, he joined Cubist (nasdaq: CBST - news - people ), saying he hoped to design a new generation of antibiotics to combat "super bugs"--deadly pathogens that are resistant to just about every drug in the antibiotic arsenal.

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