Specifically, the FDA asked that Arena demonstrate the mechanism by which lorcaserin causes mammary tumors in rats and that this mechanism is reasonably irrelevant to human risk.
You can see that files A, C, and D are now spread all over the disk which causes performance problems because the mechanism of the disk drive has to jump around to find all of the parts of the file.
This brings to mind the psychological defense mechanism called projection, which causes a person to attribute, or project, unseemly feelings and ideas to someone else.