However, Lieberman says, only Lilly agreed to provide its drug to CATIE investigators at the higher doses.
The CATIE results were released at a press conference by the National Institute of Mental Health, which funded the trial.
Worries about changes in heart rhythm that had plagued Geodon after it was approved did not turn up in CATIE.
That study, called CATIE, led to soul searching by psychiatrists over how big the advantages of the new drugs were.
Already stock analysts are starting to speculate on what CATIE might show.
From Catie Curtis to Peter Keane, Duke Levine and Lincoln Wright, Scott was being tossed around as one of the town's top collaborators.
The study was run by the same researcher who headed up CATIE: Jeffrey Lieberman, chairman of psychiatry at Columbia University's College of Physicians and Surgeons.
Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE), means for Zyprexa.
According to Lieberman, the investigators approached the makers of all the drugs being used in CATIE with proposed dose ranges that went above what the U.S. Food and Drug Administration had approved.
He was eventually switched to Zyprexa, which caused weight gain, and then to AstraZeneca 's (nyse: AZN - news - people ) Seroquel, another drug used in the CATIE study.
CATIE, which is following patients randomly assigned to an antipsychotic for two years, could finally settle the debate over whether there is an advantage--or a big risk--associated with any one of these necessary medicines, compared with the others.
Speaking on the science of blue carbon, Miguel Cifuentes, CATIE, Costa Rica, warned of the significant amounts of carbon emissions released through the destruction of coastal habitats, land use conversions and upstream disruptions, saying that coastal ecosystems maintain 75% of all tropical commercial fish species through their role as nurseries.
"The issue that is now being moved to the forefront of the government, the medical community, is we need to have objective trials to tell us whether it's worth the huge amount of money we're paying for these drugs, " says Jeffrey Lieberman , director of the New York State Psychiatric Institute and CATIE's lead investigator.
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