But without them, doctors have little idea whether or not a drug is safe or effective.
They think and act rather differently to you, but without them, life would be one long football locker room.
But without them, Mr Singh's round table seems doomed to be yet another fruitless effort to square the circle.
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But without them, the workers they represent are paying for other people to get much more generous pensions than they will ever get themselves.
They will not be rolled out until October, but even without them the tourists still managed to find some early movement, although they were aided by some indifferent shots from the England top order.
Use notes, but use them without being noticed by your audience and you will receive the maximum credit from your audience.
But without Severino to show them how to survive in the wild, that will be extremely difficult.
They would like to have more amphibious ships and a better jeep, but they can win without them.
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Police also questioned Mohammed Merah's mother and his brother Abdelkader's girlfriend, but have released them without charge, the Paris prosecutor said.
Strategies and plans provide key frameworks for action, but without money to back them up, they are just words on paper.
Technologically, the touch elements are nice, but I can live without them.
He said he knew he could no longer care for his creations if they stayed at home with him, but he felt lonely without them.
It's going to be a tough, first couple weeks without them, but we'll get through it.
"We could do it without them, but it would be a lot more work, " Baker said.
And for employing someone who can talk fast with the best of them, but without wasting a word.
You know you did them, but without a reality TV film crew shooting your every move, the IRS may not believe you.
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Bonds are a strong and important part of just about any portfolio, but owning them blindly and without consideration of long-term return is ill-advised.
Parker, the Western Conference player of the month in January, may be appreciated more without them, but said he wants them on the floor with him.
Mr Bush has called for a moratorium on the sale of uranium technologies to countries without them, but he has winked at Brazil's decision to build a uranium-enrichment plant.
But getting them through the legislature without Ms. Banerjee's support is likely to be even trickier.
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New spending commitments are unaffordable, but Mr Cameron cannot oppose them without inviting charges of callousness.
But getting stem cells to divide without them turning into other cell types is an even bigger problem.
For we know that America cannot meet the threats of this century alone, but the world cannot meet them without America.
He needed the glasses, but sometimes he could see better without them.
Preorder bonuses may now be generally accepted by the gaming public, but try to take them away without warning after handing them out?
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In words and deeds, we are showing the world that a new era of engagement has begun, for we know that America cannot meet the threats of this century alone, but the world cannot meet them without America.
And I think the President believes and I think -- without speaking for them but having read some of their comments after the meeting -- I think everyone thought it was a productive beginning in hopes of finding some of that common ground.
The heat was on and the windows were closed, but even without being able to hear them you knew that radios were playing up and down the block and that families who wouldn't otherwise consider listening to a Lindbergh rally were tuned in because of the scheduled appearance there of Rabbi Bengelsdorf.
For many white British households, the 2000s had left them without a job but with a sizeable chunk of capital in their home.
It not only offered such desktop-computer-like services as e-mail, but allowed a driver to use them without looking away from the road.
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