Their defender Brede Hangeland is a handful but when Manucho came on it was a different ball game.
Fulham had taken the lead when Brede Hangeland headed home Bjorn Helge Riise's corner from six yards out.
And Davies crossed for the third which Brede Hangeland headed in easily.
Then Boa Morte, under pressure from Brede Hangeland, put Cole clear through, but his right-footed shot was diverted to safety by Paul Konchesky.
After his side was refused a penalty when Florent Malouda was carelessly bundled over by Brede Hangeland, Ancelotti decided to bring on extra firepower.
The best opportunities the pair had were presented to them by the home side - in particularly an off-colour Brede Hangeland - but these they spurned.
Fulham pushed centre-back Brede Hangeland up into attack late on but could not avoid defeat, with Konchesky's dismissal for a tackle on Taddei rubbing salt into their wounds.
They could have gone in front inside 15 seconds when Brede Hangeland's header was superbly tipped over by Andriy Pyatov, but the Cottagers only had to wait two more minutes to nudge ahead.
Brede Hangeland nodded a corner wide, Zamora shot straight at keeper Povilas Valincius and Zoltan Gera flashed wide of the near post as the Cottagers failed to turn their increasing dominance into goals.
Suddenly the Cottagers were rampant and they went close to levelling soon after, when Alex Manninger clawed away a Brede Hangeland header, then threatened again with shots from Zoltan Gera and Bobby Zamora.
And Fulham's Brede Hangeland and Senegal defender Pape Diakhate are thought to be on Wenger's radar as he looks to shore up his shaky rearguard, although William Gallas could be on his way out of the club.
He not only rejuvenated the likes of Danny Murphy and Simon Davies, but identified unheralded talents such as Brede Hangeland and experienced players who had fallen out of favour at their previous clubs - Mark Schwarzer, Zoltan Gera, Bobby Zamora and Damien Duff to name but four.
When Kevin Doyle held off Brede Hangeland on the right there looked to be little real danger, but the Irishman clipped an enticing cross to the back post and Van Damme side-footed the ball back across a scrambling Mark Schwarzer to claim his first goal for the club.
Hodgson's carefully crafted team of budget signings (Zoltan Gera, a free transfer from West Brom), obscure European finds (Brede Hangeland from FC Copenhagen) and rejuvenated 'Big Four' cast-offs (Danny Murphy, ex-Liverpool, and former Chelsea winger Damien Duff) have negotiated 14 games on their way to their maiden European final.
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