Moments later, Cipriani burst through two tackles to score after a Waldouck half-break and Sackey's second try - after a great pass out of contact by Van Gisbergen - looked to have made the game safe for Wasps.
But after a break of serve apiece, Nalbandian dominated the tie-break and took it with a sweeping forehand pass.
Blackpool, fearless to the last, continued to attack after the break and should perhaps have made more from an early promising position but Taylor-Fletcher delayed his pass and Campbell's eventual shot was blocked.
Young scrum-half Dave Lewis, playing just his second Premiership game, made the initial break after a well worked line-out and although his attempted long pass to Iain Balshaw drifted forward, the referee let play continue.
After the break, Melling went over after a tidy Randall pass and Wildcats scrum-half Jeremy Smith was shown yellow for dissent.
Izaguirre capitalised on a slack defensive pass-back by Milne four minutes from the break and glided into the St Johnstone penalty area before calmly slotting past Smith to give the hosts a two-goal lead at the interval.
Newcastle looked no better after the break and suffered from another early goal, when Gerry Taggart played a pinpoint 50-yard pass into the path of Savage.
Gary McSheffrey replied in style just before the break, pouncing on Mark Hudson's poor pass near half-way to beat Kevin McNaughton and hit home.
The fly-half's break led to the opening try for lock Dan Tuohy and also picked off an Ospreys pass for Simon Danielli to claim the first of his two scores.
The Kiwis trailed 16-12 at the break but scored first after the restart through Hohaia and extended their advantage after a poor pass from Billy Slater gifted a try for Benji Marshall.
Wales hit back after half-time as a fine pass back inside from Jonathan Davies allowed Halfpenny to break through, then a line-out catch and drive shoved Hobbs over.
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