While not quite as "nano" as the SIM card-sized satellites that launched with the Shuttle Endeavor, the smaller-than-a-breadbox ExoPlanetSat is still pretty tiny by satellite standards, yet it packs all the necessary optics and technology required for what's known as transit observation -- that is, monitoring a star for decreases in brightness, which could indicate a planet passing in front of it.
ENGADGET: ExoPlanetSat nanosatellite to begin search for alien worlds next year