In a global study conducted by Dr. Steven Narod, senior scientist at Women's College Research Institute in Toronto, the United States had the highest rate of prophylactic mastectomy in BRCA1 and BRCA2 mutation carriers.
But for the average breast cancer patient who has neither the BRCA1 or BRCA2 gene mutation nor a close relative with breast cancer (Jolie's mother, for example, died from ovarian cancer), the risk of a new breast cancer in the nonaffected breast is less than 1%.
The 37-year-old actress previously said she decided to have the double mastectomy followed by reconstructive surgery after learning she carries a mutation of the BRCA1 gene, which sharply increases her risk of developing breast and ovarian cancer.