High levels of homocysteine are associated with faster brain shrinkage and Alzheimer's disease.

BBC: Vitamin B 'puts off Alzheimer's'

The study authors believe it was the B vitamins' effect on levels of homocysteine that helped slow the rate of brain shrinkage.

BBC: Vitamin B 'puts off Alzheimer's'

One unusual effect of the drug is that it appears to reduce the gradual brain shrinkage seen in MS patients over time, says Mundel.

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In a study published in the journal Neurology of almost 700 people born in 1936, researchers found physically active people showed fewer signs of brain shrinkage and other deterioration than those who got less exercise.

WSJ: Exercise Might Beat Puzzles for Protecting the Aging Brain

If bapi is doing what it is supposed to in terms of reducing the levels of beta amyloid and phospho-tau, and yet not improving cognition nor reversing brain shrinkage, perhaps the whole amyloid hypothesis is flawed.

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Researchers found that higher levels of physical activity were associated with less brain atrophy, or shrinkage, and less brain damage.

WSJ: Exercise Might Beat Puzzles for Protecting the Aging Brain

Using imaging, scientists have shown that meditation can improve the functional performance of specific circuits in the brain and may reduce age-related shrinkage of several brain centers, particularly those that may be vulnerable in disorders such as Alzheimer's disease.

WSJ: Doctor's Orders: 20 Minutes of Meditation Twice a Day

Imaging studies on depressed humans show shrinkage in their hippocampus, a brain region involved in learning, memory and emotion that is also a region where much neurogenesis occurs.

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