Gen-Probe, like Biosite a San Diego firm, made its mark in 1985 with a test for Legionnaires' disease.

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Small, prosperous diagnostic companies are in short supply, which explains the battle for Biosite and the high acquisition price.

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Waller expects Biosite's earnings to increase 17% annually for the next five years.

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According to Gibbons, Biosite's heart diagnostics business could have 73% growth this year.

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Here Biosite has been one of the most successful players.

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San Diego-based Biosite has another plus: profits.

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Biosite (nasdaq: BSTE - news - people ), a San Diego medical test maker that has appeared repeatedly on the Forbes 200 Best Small Companies list, has been swallowed up by another medical diagnostics outfit.

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Inverness, best known for its home pregnancy and fertility tests, beat out Beckman Coulter (nyse: BEC - news - people ), a Fullerton, Calif. medical test maker that launched a takeover attempt of Biosite in March.

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Individual stocks Spear currently has on his watch list: Central European Distributors (nasdaq: CEDC - news - people ), Biosite (nasdaq: BSTE - news - people ), Fossil (nasdaq: FOSL - news - people ) and Symantec (nasdaq: SYMC - news - people ).

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Generic drugmaker Able Labs (nasdaq: ABRX - news - people ) is also high on Oberweis' list of top buys, along with chemical and pharmaceutical firm Aceto (nasdaq: ACET - news - people ) as well as medical testing company Biosite (nasdaq: BSTE - news - people ).

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