Nearly all drugs work by binding to proteins that help cause disease.

FORBES: Magazine Article

Most drugs work by binding to proteins like locks.

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The system could, for example, be used to explore the binding between Helicobacter proteins and those in the stomach cells that it attacks, in order to find targets for new drugs to block ulceration.

ECONOMIST: Genomics

By binding to RNA, antisense prevents proteins involved in disease from ever being created.

FORBES: Magazine Article

Recently, however, Carlos Bustamante, a biophysicist at the Howard Hughes Medical Institute at the University of Oregon, in Eugene, and his colleagues there and at the University of California, Santa Barbara, have found a way to observe proteins as they search for their binding sites.

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The researchers in this study examined the geometric structure and behaviour of one of the rotavirus's surface proteins, called VP4, which plays a key role in binding on to the surface of a target cell, and breaking through its membrane.

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