In the early 1990s, dermatologist Kevin Cooper, then at the University of Michigan, observed that the binding of CD-2 to LFA-3 set off psoriasis' chain reaction.

FORBES: Skin Deep

These work by binding chemically to that enzyme's active site to inhibit its action. (Protease cuts the raw chain of virus protein produced by a subverted cell into functional molecules.) However, the mechanism is not quite identical.

ECONOMIST: Nanotechnology in biology