But what's big to a small biotechnology company is not so big for a drug giant, even one that has notable gaps in its drug pipeline.
But regulators still tend to imagine that power will flow in one direction only: from big plants to small consumers.
Like the talent on and off camera, viewers too have embraced the shift from big screen to small.
Other investors, though, are shying away from big exposures to small markets.
Issues with running water, scarce electricity and more contributed to headaches big and small, according to passengers and their loved ones.
Is it so hard to picture this migration: Big-box to small-box, to no-box at all?
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Though he spent his legendary career speaking in front of thousands, VJ managed to deliver a number of very big messages to the small crowd that occupied gapCon.
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And his working party supports tax breaks for equity incentives to lure managers from big companies paying big salaries, to small companies that cannot yet afford generous pay.
The San Francisco-based organization founded by Brent Schulkin organizes campaigns that harness the collective purchasing power of consumers to incentivize companies, big and small, to become more socially responsibile.
Then we have a company called Shahmoon TV whose Street Ads use large HD video posters to bring big-screen advertising to small scale stores, enabling businesses to interact with passers-by, feed live information, and communicate directly with those consumers.
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The pressure on firms big and small to report on their non-financial activities is significant.
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They spent the next six months cold-calling techies at companies big and small to find out what kind of Webware they needed.
By contrast, the race of investors big and small to grab a piece of the Busang action was not the least bit irrational.
From a big initiative to a small gesture, Memorial Day is the perfect time to offer a simple act of kindness to our veterans and military families.
Sensing the need for clubs in markets big and small to provide the service, the company rolled out a "managed service" option, with which teams essentially lease the service instead of buying.
She and other MPs argued that the idea is very much in the spirit of the Big Society to help small business and social enterprises and that there was a danger of the market for Green Deal energy improvements being dominated by a few corporate big boys.
But if they are to succeed, companies both big and small will first have to assuage growing concern over the privacy issues associated with collecting information about people's movements.
Africa's governments have recognised their responsibility to put in place the policies and investments which will enable the continent's farmers, big and small, to provide the food needed.
And getting that balance right has less to do with big government or small government than it has to do with smart government.
It still may be impossible to estimate exactly how big (or small) the eventual cost to the drugmaker will be.
As a consumer, I think we should be able to buy a big soda without having to buy two small ones.
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With our training we have been able to perform search and rescue for missing persons, provided rehab to firefighters working fires big and small, run shelters for persons displaced due to hurricanes, and even assisted with assessing damage due to tornadoes and severe storms.
So there had been progress in that the -- more people now are aware of what the playing field looks like, where the compromises can be found, and what it takes to build upon a smaller package to the biggest possible package, and the hard choices that getting from small to big require.
But, if it continues to Think Big, Start Small and Learn Fast, Google will accelerate the development of driverless capabilities worth trillions to society.
It became harder for small banks to challenge big banks, because regulations disproportionately increased small banks' cost - which is partly why there is lamentably inadequate competition in banking today (many would say).
Other disasters were either too big or too small to develop this kind of interest.
Mists of Pandaria adds new content and makes some big and small changes to World of Warcraft.
Marketers big and small want to get more embedded in their local communities.
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