The big cost lever for ACOs is successful treatment on the first hospital admission, avoiding re-admission.
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The lure of getting money early can blind people to the big cost down the road.
All this implies big cost savings, as well as greater convenience for the patient.
But there is quite a big cost of being insured by the banks against those risks.
But it's a big cost-saver for Wasun Chantratita, chief of virology and molecular microbiology at Mahidol University in Bangkok.
That particular business is not capital-intensive, with the only big cost being compensation.
Giving patients warfarin involves a whole industry of testing, and it represents a big cost to the medical system.
If its as efficacious as a marketed mAb, then of course as it will also have big cost-of-goods advantages.
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The big cost, the reason more than 100 Fort Payne mills have shut down recently comes in the next step.
The Mail's making some money out of free content online, while The Guardian's got big readership at a big cost.
Local manufacturing and distribution should bring a big cost advantage over Fuji, and lots of goodwill from the Chinese government.
Such a partnership could see big cost savings for the carrier, by herding short-haul passengers into trains and focusing on more profitable long-haul plane trips.
But both companies are in the midst of big cost-cutting programs.
Experts cite strong competition for faculty, student demand for state-of-the-art classrooms and facilities, and a decline in federal support for research facilities as the big cost drivers.
Claims administration is another area where many providers would need to outsource functions (a big cost that most would rent but not buy) to administration service companies.
At the moment, the various plans cost the firm roughly the same, but Mr Ness believes that defined contribution will lead to big cost savings in the long run.
Present low-carbon energy deployment strategies assume that greater economies of scale will drive big cost reductions, but the historical record suggest that this is less the case than normally assumed.
As if to confirm this, few of this week's mergers envisage big cost-savings as their main objective (the link-up of two American insurers, Unum and Provident, may be an exception).
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Prince has been trying to make things right by shuffling executives and putting a big cost-cutting plan in motion, but that hasn't stopped speculation that the company would be better off broken up into pieces.
Indonesia enjoys a big cost advantage over its main competitor, Malaysia, as it does over Australia in coal for power stations, another commodity where demand, led by China and India, is expected to grow hugely.
But, given the huge number of banking outlets on Britain's high streets, it is hard to avoid the conclusion that there is indeed scope to achieve big cost cuts by merging some chains and eliminating overlaps.
It is also grappling with a big cost overrun on another of its top priorities - the James Webb Space Telescope - and for which the shortfall will have to be picked up by programmes across the agency, perhaps even human spaceflight.
Capital Costs: There is going to be a big capital cost to upgrade the refineries.
Airfreight is a big added cost for races outside Europe, so halving the footprint and weight, versus the previous solution significantly reduced costs.
Changes in the big tooling cost real money.
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And there has been a lesser but still striking increase in the cost of insuring French government debt, which looks like a contributor to the big rise in the cost of insuring the debt of big French banks such as Societe Generale.
But it's more than automobiles and explosions that will cost big bucks this pilot season.
But that will cost big money and any such return would have put me closer to -or even over- the insurance cap.
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