That didn't stop either drug from capturing a big chunk of its predecessor's sales.
Wyeth owned a big chunk of biotech concern Immunex , which Amgen bought last year.
And a big chunk of pay goes to normal employees, not masters of the universe.
Just make sure you save a big chunk of that future income when it comes!
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If a generic were to get through, a big chunk of Provigil's sales would vanish.
That is when Buffett bought, for very little, his first big chunk of this company.
Not a big chunk of change, but Biscoe can't afford to gripe about it.
That is when Buffett bought his first big chunk of this property for very little.
When a home loses its value, a family loses a big chunk of their wealth.
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Mumbai is also the origin of a big chunk of India's total advertising spending.
Six thousand businesses lost, from an economy of that size, is a big chunk.
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But he has gone a step further, replanting a big chunk of his 400-hectare ranch.
That would leave a nice big chunk of those 150 hectares free for office buildings.
To help cover its losses, Amaranth also sold a big chunk of its leveraged loans.
But this partly reflects the choice of firms to pay out a big chunk of their earnings.
If the stock market crashes, you want to have a big chunk of your portfolio in bonds.
It would repudiate Mr Takano's strategy by demanding that he return a big chunk of their money.
One reason the poor learn so little is that a big chunk of school spending is wasted.
So they sign players to contracts that defer payment of a big chunk of the player's salary.
So a big chunk of the 20, 000 who are already down there are being paid by BP.
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Giving away a big chunk of the upside in stocks during these rallies will damage your long-term return.
Shaw, the big hedge fund firm, is said to have axed a big chunk of its staff.
Daniel Yergin of Cambridge Energy Research Associates says that affects a big chunk of the nation's energy supply.
It is true that dividends, rather than capital appreciation, have provided a big chunk of long-term equity returns.
Developers are a big chunk of the economy-accounting for 33% of total investment in China's fixed assets last year.
Many Chinese save a big chunk of their incomes for a raining day.
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Health Savings Accounts will let patients own and control a big chunk of the dollars spent on health care.
Learn the basic functionality of a NoSQL database (you can learn a big chunk of mongoDB in a day).
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As the leader, Bharti is getting a big chunk of this growth, adding some 700, 000 new customers every month.
They have already captured a big chunk of the solar market partly because we fell down on the job.
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