To be fair, the report also makes a number of positive observations about progress towards collaboration and the way some examples the researchers looked at had improved communication and understanding, led to better decision-making and facilitating best practice.

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Already, he says, the loss of blockbuster products like Pfizer's Lipitor for high cholesterol, the world's best-selling drug, and Eli Lilly's Zyprexa for schizophrenia, is shaping decision-making at big drug makers.

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The presidency's strong powers make it particularly important that decision-making is based on the best available advice and is exercised with scrupulous clarity and care.

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Shares in the Medicines Company were buoyed by a court decision related to the patents on its top-seller Angiomax, making it the best-performing biotechnology stock in August.

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Already, he says, the loss of blockbuster products, like Pfizer's Lipitor for high cholesterol (the world's best-selling drug) and Eli Lilly's Zyprexa for schizophrenia, is shaping decision making at big drug makers.

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More often than not, the explanation is that the 401(k) investment decision-making process at large companies has been corrupted and, contrary to fiduciary duties, the best interests of employees are not being solely pursued.

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And what we're hoping to do is at least some of the decision-making based a little bit more on what are the engineering plans that determine this is the best project to go forward.

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