He notes that Geodon sales never took off because it causes a change in the electrical rhythms of the heart.

FORBES: ADA Takes On FDA Over Schizophrenia Drugs

Yet Vitravene, a locally injected drug, fell short of proving antisense's broader promise, and it never took off because of competition from AIDS cocktails.

FORBES: Antisense and Sensibility

According to Brass, concepts such as the paperless office never took off because the industry has always focused on the creation of, but not the consuming of, information.

CNN: Microsoft banks on ClearType to spur electronic books

It's akin to expecting a Mercedes owner to upgrade merely because he just paid off the car loan--never mind that his S500 runs just fine.

FORBES: The Customer's Revenge

As a result, the seasonally adjusted figures in the fall should benefit from a smaller number of construction layoffs, not so much because construction is growing, but because the workers who would normally be laid off in the fall were never hired in the spring.

FORBES: Seasonally Adjusted Jobless Claims

So I think it's the one that is easiest to anticipate and see off in the distance because the funny thing is that Henry Aaron never got this kind of glowing praise when he was playing, and not even 10 years after he retired.

NPR: Bonds' Approaching Triumph Has Mixed Meaning

But she pulls off the downtempo ''Mr. Know It All'' -- because you're never too old for a good wag-your-finger-at-the-boys song.

CNN: Review: Kelly Clarkson's 'Stronger'

As with the perennial struggle over the horrors of medical malpractice, the question of whether or not to screen for cancer is one of those health-care Holy Wars that will never be resolved merely shunted off into another who-pays economic grind-down because where data ought to rule, emotion will always overrule.

WSJ: Are Doctors Screening Too Much for Disease?