The mission has major significance because it marks a big change in the way the US wants to conduct its space operations.
It needs to change, because the church has big problems, most of which existed before 2002 and have nothing to do with sex abuse.
ECONOMIST: The pain of the sex-abuse scandal may be helping the church
Mr Delay explained that the issue of water scarcity was closely linked to climate change because "one of the big impacts will be the threat to freshwater supplies".
And if you think that public education will never change because it's too big, I'd point out that the music business looked like an invincible Goliath before digital technology raised its slingshot.
That devotion could cut both ways, because the new WRX is a big change in approach from the current one.
FORBES: New York Auto Show: Subaru Unveils The New Subaru WRX
However, this season will be a big change for our boys because, for the past two seasons, they have been challengers.
"For the patients it is a really big deal, because it may change the whole way the disease unfolds in them, " says the University of Miami's Jay Skyler.
Opponents have locked onto climate change because they can portray it as a great big scary unknown.
FORBES: Mother Nature to Keystone Pipeline Protesters: Chill Out!
Called Mountain Lion, it won't be as big a change as Windows 8, partly because Apple already has integrated a lot of touch gestures and tablet-type features into the Mac using the touch pad, and has given no indication it plans touch screens.
And the playoff system only marginally adds choice because allowing a team from outside the big six conferences does not change the balance of power and resources.
FORBES: Maryland and Rutgers Move to Big Ten: Savvy Realignment or Priorities Misalignment.
We need to change that, because those traditional payroll jobs aren't coming back in big numbers.
We may not be able to change everything all at once just the way we want it, because this is a big, complex democracy, and not everybody has got a same opinion.
But I think it's also because of an assessment that American troops would not be welcome in Lebanon, which is a very big change in the attitude there.
应用推荐